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24x7Report > Blog > Sports > 2025 CFL picks, betting odds, predictions: Proven expert reveals predictions for every game on Week 6 schedule
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2025 CFL picks, betting odds, predictions: Proven expert reveals predictions for every game on Week 6 schedule

Last updated: 2025/07/10 at 11:35 PM
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Calgary Stampeders at Saskatchewan Roughriders (Friday, 9 p.m. ET)Ottawa Redblacks at Hamilton Tiger-Cats (Saturday, 7 p.m. ET)BC Lions at Edmonton Elks (Sunday, 7 p.m. ET)

The Saskatchewan Roughriders will look to remain undefeated after they host the Calgary Stampeders within the CFL sport of the week on Friday at Mosaic Stadium in Regina. 

The Roughriders (4-0), who’re coming off a bye week, are the league’s final remaining undefeated group. With a win on Friday, they’d match the franchise’s finest begin to a season since 2013 when Saskatchewan went 11-7 in the course of the common season and gained three in a row to seize the Gray Cup. Final season, the Roughriders additionally began the season 4-0, however misplaced 35-20 to the BC Lions in Week 5.

Saskatchewan beginning quarterback Trevor Harris, who missed the group’s final sport whereas in concussion protocol, has been cleared to play and is about to begin on Friday. The 39-year-old quarterback and two-time Gray Cup champion has accomplished 58 of 80 passes for 806 yards and 5 touchdowns in opposition to three interceptions this season. He led the group to victories over Ottawa, Hamilton and Toronto earlier than Jake Maier directed the Roughriders to a 37-18 win over the BC Lions on June 28.

Friday’s sport will pit the CFL’s finest offensive group in opposition to the league’s finest defensive one. Saskatchewan is tied for the CFL lead in scoring offense (29.3 factors per sport), whereas Calgary leads the league in scoring protection (20.3). Final week the Stampeders allowed simply 16 factors to the reigning West Division champions, the Winnipeg Blue Bombers, in a dominant 37-16 victory. Calgary (3-1) is tied for the second finest report within the CFL.

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The Roughriders are 5.5-point favorites, and the whole for factors scored is 53.5.

On Saturday within the CFL, the Hamilton Tiger-Cats (2-2) will look to win their third straight sport after they host the Ottawa Redblacks (1-4). The Tiger-Cats have scored a mixed 86 factors over their final two video games, which embody a 51-38 blowout over the reigning Gray Cup champion Toronto Argonauts final week. Hamilton has gained 11 of the final 13 conferences between the groups, together with the previous six at Hamilton Stadium.

The Tiger-Cats are 5.5-point favorites over Ottawa, and the whole for factors scored is 55.5.

Week 6 concludes on Sunday with a matchup between the 2 groups on the backside of the West Division, the BC Lions (2-3) and Edmonton Elks (1-3). This would be the second sport between the Lions and Elks this season; BC gained the season opener 31-14. Since then, nevertheless, Edmonton quarterback Tre Ford has accomplished 60 of 82 passes (73.2%) for 772 yards and 5 touchdowns in opposition to just one interception. 

The Lions are 2.5-point favorites over the Elks, and the whole for factors scored is 51.5.

SportsLine soccer skilled Emory Hunt has gone 13-7 on his CFL picks this 12 months and has revealed his choices for Week 6, together with against-the-spread predictions and leans on the whole of every sport.

Hunt is the founder and CEO of Soccer Gameplan, which has been supplying evaluation of all ranges of soccer since 2007. He’s a former working again for the Louisiana Ragin’ Cajuns and is aware of the sport from a participant’s perspective. Hunt’s dedication to evaluation of all ranges {of professional} soccer helped him crush the CFL, XFL, and USFL in 2023, posting a mixed ATS report of 98-73 in his SportsLine articles.

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Calgary Stampeders at Saskatchewan Roughriders (Friday, 9 p.m. ET)

Choose: Calgary +5.5
Lean: Over 53.5

That is the sport of the week, for my part. Calgary is coming off of a 37-16 thumping of the Blue Bombers, whereas the Riders are coming off of a bye week. In its final sport, Saskatchewan pounded the BC Lions 37-18. I count on a ton of factors being scored right here and for the sport to be a back-and-forth affair. The Stamps have sufficient offense to maintain this sport inside the 5.5-point unfold.

Ottawa Redblacks at Hamilton Tiger-Cats (Saturday, 7 p.m. ET)

Choose: Ottawa +5.5
Lean: Over 55.5

Dru Brown was again within the lineup final weekend at quarterback for Ottawa, and he began to seek out his groove as the sport went on. As a result of this can be his second sport again, I count on him to look extra just like the man we anticipated coming into the season. Meaning the offense will look far more cohesive than it did within the first half in opposition to Edmonton. This level unfold feels a bit an excessive amount of. I feel this sport comes all the way down to a late subject aim.

BC Lions at Edmonton Elks (Sunday, 7 p.m. ET)

Choose: Edmonton +2.5
Lean: Over 51.5

This needs to be a terrific matchup between two Canadian beginning quarterbacks. Elks QB Tre Ford has improved a lot during the last three video games, culminating in Edmonton’s first win of the season final weekend. Proper now, there’s nonetheless an excessive amount of inconsistency from BC Lions quarterback Nathan Rourke for me to belief him on this highway sport in opposition to a assured Elks squad.

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TAGGED: Betting, CFL, Expert, Game, odds, Picks, Predictions, Proven, Reveals, Schedule, week

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