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Reading: 2025 college football Week 6 picks against the spread, odds, lines, trends: Expert reveals best bets
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24x7Report > Blog > Sports > 2025 college football Week 6 picks against the spread, odds, lines, trends: Expert reveals best bets
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2025 college football Week 6 picks against the spread, odds, lines, trends: Expert reveals best bets

Last updated: 2025/10/01 at 2:16 PM
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Prime faculty soccer predictions for Week 6 Methods to make faculty soccer picks for Week 6School soccer odds for Week 6 notable video games

The Week 6 faculty soccer odds board is loaded with high-profile matchups that might have potential School Soccer Playoff implications. Among the many notable Week 6 faculty soccer betting strains is No. 10 Alabama (-10.5, 55.5) vs. No. 16 Vanderbilt, No. 18 Florida State vs. No. 3 Miami (-4.5, 53.5), No. 9 Texas (-6.5, 41.5) vs. Florida, Boise State vs. No. 21 Notre Dame (-20.5, 62.5), and No. 11 Texas Tech (-11.5, 50.5) vs. Houston. The most important Week 6 faculty soccer unfold sees the Oklahoma Sooners as 45.5-point favorites at dwelling over the Kent State Golden Flashes.

How must you make faculty soccer picks for these video games, and what are the most effective unfold, complete and money-line picks to incorporate in faculty soccer greatest bets? Earlier than locking in any Week 6 faculty soccer picks, make sure to see the college football betting guide from legendary Vegas handicapper Bruce Marshall. 

New customers can even goal the newest Underdog promo code, good for $100 in site credits when you play $5 with the promo code CBSSPORTS2 in choose states.

For years Vegas-based Marshall was synonymous with The Gold Sheet, the well-known sports activities betting publication. He has additionally received varied handicapping titles and in addition is engaged on a number of e-book tasks. Marshall crushed his 2024 faculty soccer betting picks, going 64-43 and returning greater than 16 models, ending the season as SportsLine’s prime skilled. Anybody following might have seen large returns. 

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Now, utilizing his Tech Nook approach that evaluates all of the tendencies, Marshall has turned his consideration to the newest faculty soccer odds for Week 5 and evaluated every matchup. You can head to SportsLine to see every pick.

New customers can even goal the DraftKings promo code, which gives new customers $200 in bonus bets with a winning $5 wager:

Prime faculty soccer predictions for Week 6

One of many prime faculty soccer picks Marshall is recommending for Week 6: He is backing Vanderbilt (+10.5) to remain throughout the unfold at dwelling towards Alabama at Bryant-Denny Stadium in Tuscaloosa at 3:30 p.m. ET on Saturday. He additionally likes the Over (55.5) to hit.

Alabama (3-1) was blown out in its season opener, shedding to Florida State 31-17 in Tallahassee. The Tide has rebounded with three straight wins, together with a 24-21 victory over Georgia in Week 5. Vanderbilt (5-0) has received all 5 of its video games in 2025 in blowout style, together with a 31-7 assertion win over South Carolina. Switch quarterback Diego Pavia has been excellent, throwing for 1,211 yards, 13 touchdowns, and three interceptions, and speeding for 294 yards and two scores.

“The Commodores after all scored that mighty 40-35 upset of the Tide final yr for first collection win since 1984,” Marshall mentioned. “Vandy is 12-5 vs. line since final season, and in addition boasts the arrival of NMSU switch Diego Pavia, who’s 10-2 as canine since final season. Tide has received and coated three straight since FSU loss and has really coated final 5 at Tuscaloosa. Vandy is on a 6-2 Over run since late 2024. Tech edge goes to Vanderbilt and the Over, primarily based on current and totals tendencies.” Go to SportsLine to see all of Marshall’s picks. 

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 Methods to make faculty soccer picks for Week 6

Marshall has evaluated each different matchup and he is discovered a important 7-0-1 ATS pattern in one other Week 6 sport. Get betting analysis for each matchup at SportsLine, and use promo code CHAMPIONSHIP to get your first month for $1.

So what faculty soccer picks are you able to make with confidence, and what alarming pattern do it is advisable to learn about this week? Try the newest faculty soccer odds beneath, then visit SportsLine to see which teams to back, all from the legendary Vegas expert who has won multiple handicapping titles and went 64-43 last season, and discover out.

School soccer odds for Week 6 notable video games

See full Week 6 college football picks, odds, predictions here
(odds topic to alter)

Thursday, Oct. 2

Sam Houston vs. New Mexico State (+2.5, 52.5)

Friday, Oct. 3

Charlotte vs. South Florida (-27.5, 54.5)

West Virginia vs. BYU (-18.5, 47.5)

Saturday, Oct. 4

Kentucky vs. Georgia (-20.5, 48.5)

Wisconsin vs. Michigan (-16.5, 42.5)

Air Drive vs. Navy (-11.5, 51.5)

Clemson vs. North Carolina (+14, 46.5)

Texas vs. Florida (+7, 41.5)

Boise State vs. Notre Dame (-20.5, 62.5)

Virginia vs. Louisville (-7, 61.5)

Vanderbilt vs. Alabama (-10.5, 55.5)

Miami vs. Florida State (+4.5, 53.5)

Minnesota vs. Ohio State (-23.5, 44.5)

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TAGGED: Bets, College, Expert, football, Lines, odds, Picks, Reveals, spread, Trends, week

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